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KMID : 0614619930250030603
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Korean Journal of Gastroenterology
1993 Volume.25 No. 3 p.603 ~ p.610
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Two Cases of Amanita mushroom Poisonings
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안병민
김진일/김병욱/양진모/이봉수/이영길/심규식/정규원/김부성
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Abstract
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Fatal cases of mushroom poisonings are mostly caused by Amanita species in Korea. Amanita mushrooms induce severe liver damage by cyciopeptide toxins which are thermostable.
Human victims of acute Amanita polsoning usually undergo typical three phases. The gastrointestinal symptoms of colicky abdominal pain. vomiting, watery diarrheaa begin 6012 hr after ingestion of musinrooms. In most cases, gastrointestinal
symptoms
regress spontaneously and then clinical signs of severe hepatic injury develop.
The histopathological findings of acute liver injuries are acute hemorrhagic necrosis of parenchyma, coagulative necrosis, vacuolated degeneration. Micro-vesicular fat droplets, And yellow atrophy in the literature. However, the ultrastructural
findings
on human victim have been rarely reported.
In Korea, total number of reported human victims of Amanita poisoing in the literature was below 60 and there was no precise description on the subspecies of genus Amanita except only one in 1987.
Recently, we experienced two cases of mushroom poisomngs by Amamta virosa. Thus we report the clinical findings of the patients with the histological feature of liver injury using light and electron micorscopy.
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